Wendy and Bebe are friends again. I guess Bebe got over her shoe fetish.
"Wendy and Cartman are gonna fight after school" - If you have the first airing of the episode, Bebe actually says "Rodney and Cartman are gonna fight after school," but of course the audio was fixed quickly.
Remember when Wendy and Cartman worked together and Cartman fell for her, and she turned him down in the end? It's not brought up in the episode, but you gotta wonder how those two will treat each other in the future.
Goths listen to AC/DC ("I don't ever remember AC/DC...")? Google tells me that they do, heh. Of course jocks would listen to the band.
When the Goth kids mentioned AC/DC and Galahad, they were calling Stan a pussy. AC/DC was used as an example of guys who wouldn't let other dudes beat up on their girlfriends. In Arthurian legend Galahad defeats rival knights apparently without effort, but Stan didn't lift a finger to stop the fight from happening.
Trey works Breast Cancer Awareness Month into the plot, as this originally aired in October 2008, but he doesn't do much with it except use it as a way for Principal Victoria to let Wendy beat the crap out of Cartman.
Movie references!
Snatch - the freeze-frame featured in the fight
There Will Be Blood - Wendy's last line, "I'm finished!"
A remix of "Fucking in the Bushes" by Oasis is the song used during the fight.
You know that Ike was in kindergarten- nevermind, I forgot Ike started kindergarten when Kyle and friends started 4th grade.